Summary of #PHTwitJC 27: ‘Greening vacant lots to reduce violent crime: a randomised controlled trial’

On Wednesday 31st July, #PHTwitJC discussed:

GARVIN E, Cannuscio C, Branas C. (2013) Greening vacant lots to reduce violent crime: a randomised controlled trial. Inj Prev 19:198-203 doi:10.1136/injuryprev-2012-040439.

The full text can be accessed at this link: http://injuryprevention.bmj.com/content/19/3/198.full

Discussion:

The discussion was structured around the five questions in the previous paper summary post.

1.Were the aims of this study clear? (consider whether it clearly defined the population, intervention, outcome and comparison)

The participants felt that the aims of the paper were clear and justified by a strong introduction section.

A few words used in the paper were new to participants – potentially due to the study using US terms – but they were either well defined in the paper or were easily understandable.

“I thought that the aims were clear too – ‘greening’ was new to me but nicely defined” – @duncautumnstore

“The terminology felt very American – would we call them ‘lots’ in UK? What would we say instead? ” – @carotomes

2.Was the methodology appropriate?

Randomised controlled trials (RCT) are one of the strongest study designs, and it was agreed that it was an appropriate method here.

“RCT was appropriate to assess causality between greening and crime, although unsure whether truly randomised…” – @carotomes

Participants noted that there was some ambiguity about the randomisation method, and it was hard to pick out from the paper how many clusters of lots were ultimately randomised.

“E.g. P199 each cluster lot was viewed by PHS to determine if appropriate to send for greening authorisation? I didn’t fully understand this – seemed like a vetting process prior to randomisation, also unclear of randomisation method.” – @carotomes

“yes, it was a little unclear. I couldn’t work out how many clusters were randomised in the end” – @duncautumnstore

There was some discussion about whether the method used to group lots meant that the design was closer to a cluster RCT. It was noted that this would still be a strong design, but that that also more information should be provided when conducting a cluster RCT.

“I wondered that. Or whether it was closer in design to cluster-RCT” – @duncautumnstore

“absolutely – it was a cluster RCT rather than RCT. But no discussion of heterogeneity assessment” – @carotomes

Several of the difficulties of conducting an RCT on a built environment intervention were also discussed, as these may account for some of the compromises in study designed.

“not often you get the circumstances to do an RCT on the built environment, so maybe some compromises had to be made.” – @duncautumnstore 

“[Pennsylvania is] big enough to fit a few more clusters into the trial… perhaps financial reasons, but we don’t know from the paper” – @duncautumnstore

3.Did the analysis use appropriate methods?

There was some discussion over the difference-in-differences method used, and whether any other statistical methods could have been used instead.

Participants found the difference-in-differences method intuitive, however, in the experience of the participants it rarely appeared in statistics text books. This made it harder to judge what the strengths and limitations are of using difference-in differences in this paper.

“I’d not come across difference-in-differences before. Not sure on its strengths and the right circumstances to use it.” – @duncautumnstore

4.Do you believe the results? The study reports non-significant reductions in crime and improvement in perceptions of disorder, but also a significant improvement in residents perceptions of safety, what could explain these findings?

The participants discussed that reductions in crime from green spaces seemed plausible, but given that there was some uncertainty over the methodology used in this study it was difficult to be more confident about some aspects of the results.

“I don’t know if I can be confident as I’m unclear about their methodology and analysis” – @carotomes

The authors also highlighted the preliminary nature of these results in the paper, and aspects of this were discussed by the participants. 

“I get the feeling that the authors were a little tentitive from drawing too many certain conclusions too” – @duncautumnstore

“[the] authors themselves recognise the limitations of small sample and unrobust data” – @carotomes

“they use phrases like ‘preliminary evidence’ and advocated larger trials” – @duncautumnstore

The participants identified the potential for bias in the way that the questionnaire was used to measure the resident’s perceptions of safety.

“survey on perceptions of safety and violence primes interviewees of research purpose!” – @carotomes

5.What implications do the findings have for public health practice & policy?

The discussion of the implications referred back to the tentative nature of the findings. It was suggested that the focus of the paper could have been on the usefulness of the method rather than the results.

“feels like focus on paper should’ve been ‘is this method practical to test Q’ in prep of larger trial” – @carotomes

Research findings are essential for advocating for good public health, but one participant felt that the results from this paper weren’t striking enough to help advocate for green spaces.

“an important methods paper, but I don’t think the results are striking enough to be the one used to advocate for green spaces” – @duncautumnstore

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Confirmed injury prevention paper for #PHtwitJC 27

The winning paper in the poll for the 27th #PHtwitJC is:

GARVIN E, Cannuscio C, Branas C. (2013) Greening vacant lots to reduce violent crime: a randomised controlled trial. Inj Prev 19:198-203 doi:10.1136/injuryprev-2012-040439.

The full text can be accessed at this link: http://injuryprevention.bmj.com/content/19/3/198.full

The discussion will take place on twitter on Wednesday 31st July, at 8pm BST (GMT+1).

All are welcome to join the discussion at the Twitter Hashtag #PHTwitJC. If you have not joined a Twitter chat before, please see the ‘about’ tab above for some tips.

Introduction:

Green space can have a wide range of public health benefits, such as improving mental wellbeing and creating an area that are usable by the local community. Depending on the nature of the green space it can be used for play or exercise, leading to further benefits for the people and community who use it. From an aesthetic point of view, green spaces can be used to break up the monotony of urban environments and make it a lot more interesting and pretty!

The importance of green spaces is often reflected in policy too. For example, in England the use of outdoor spaces (including green spaces) is one of the public health outcomes indicators. Based on previous research, the specific role of green spaces in preventing violence is highlighted in ‘A public health approach to violence prevention for England’.

This study is the first randomised controlled trial that examined whether converting disused areas into green spaces can reduce violence.

Paper Summary:

Method
The study used a Randomised Controlled Trial. 2,814 vacant lots were included in the study from a larger database of 54,132 vacant lots in Philadelphia in 2008. Lots in the same area were grouped together and then randomly assigned to receive ‘greening’ or to lie in their current state.

Intervention
Vacant lots were ‘greened’ by the Pennsylvania Horticulture Society (PHS) in May 2011. The greening process was done to a standard where PHS; removed debris, improved the soil, planted grass and trees and built a low wooden fence with opening around the lot. The site was maintained the site every two weeks. There is a before-and-after image in the paper.

Results
Reported crime – in the intervention area, 209 crimes were reported in the three and a half months before greening and 266 were reported during the same time period after. During the same time period at the control site, there was an increase in from 460 reported crimes before, to 521 crimes after. This meant that the unadjusted net difference-in-differences estimate was -4 at the greening site, which was a non-significant change (see table 2 for a break down of different types of crime).

Perceptions of disorder – A self-reported neighbourhood disorder scale was used to collect resident’s perceptions of disorder. An unadjusted difference-in-differences estimate was used again, and found that there was a reduction in perceptions of disorder at the intervention site compared with the control site. A regression-adjusted difference-in-differences estimate found that the differences were not significant.

The authors highlighted that a component of the perceptions of disorder scale that measures perceptions of safety found that this improved in the intervention site, and that this finding was highly significant when using both unadjusted and regression-adjusted difference-in-differences estimates.

Conclusion
The authors cocluded that the study ‘provides preliminary evidence that vacant lot greening may reduce violent crime and increase perceptions of safety’.

However, the authors also argued that larger trials would need to be conducted:

“Based on the findings of this smaller trial, these larger randomised trials will likely require hundreds of vacant lots in multiple study arms (greening intervention, trash pickup only and control) to have sufficient statistical power and detect meaningful effect sizes.”

It was suggested that this study provides a model for the larger trials.

Discussion Points:

1.Were the aims of this study clear? (consider whether it clearly defined the population, intervention, outcome and comparison)
2.Was the methodology appropriate? (for instance: were appropriate methods used to identify vacant lots, randomise the lot, and select local participants?)
3.Did the analysis use appropriate methods? (for instance: was the unadjusted difference-in-differences suitable for the comparisons)
4.Do you believe the results? The study reports non-significant reductions in crime and improvement in perceptions of disorder, but also a significant improvement in residents perceptions of safety, what could explain these findings? (for instance: chance, bias, or confounding?)
5.What implications do the findings have for public health practice & policy? (for instance: are the results applicable outside the US? What further research needs to be conducted?)

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Injury Prevention – cast your vote for a paper #PHTwitJC 27

The next #PHtwitJC is on Wednesday the 31st July at 8.00pm (BST). All contributions are welcome – and this time @duncautumnstore will be a guest presenter.

The topic for the journal club is injury prevention. Injuries are often grouped into categories such as road injury, self-harm (including suicide), falls, interpersonal violence, drowning, or poisoning. Together they represent a major burden on health – traffic injuries alone are the eighth most common cause of death world-wide.

Whilst there are many interventions that limit the severity of injuries after or during the event that causes them, the papers selected for this journal club look at several different ways of preventing injuries from occurring, such as though advocacy, legislation, or the design of the built environment.

The full citations and URLs are listed below the poll.  Please vote for your favourite that you’d like to discuss in the journal club. Voting will close late on Monday 22nd July.

Full references and links

ALLEN E, Hill A, Tranter E, Sheehan K. (2013) Playground Safety and Quality in Chicago. Pediatrics Vol. 131 No. 2 February 1, pp. 233-241. doi: 10.1542/peds.2012-0643. Full text link

CHAPMAN S, Alpers P, Agho K, Jones M. (2006) Australia’s 1996 gun law reforms: faster falls in firearm deaths, firearm suicides, and a decade without mass shootings. Inj Prev 12:365-372 doi:10.1136/ip.2006.013714. Full text link

GARVIN E, Cannuscio C, Branas C. (2013) Greening vacant lots to reduce violent crime: a randomised controlled trial. Inj Prev 19:198-203 doi:10.1136/injuryprev-2012-040439. Full text link

LYONS RA, Kendrick D, Towner EML, Coupland C, Hayes M, et al. (2013) The Advocacy for Pedestrian Safety Study: Cluster Randomised Trial Evaluating a Political Advocacy Approach to Reduce Pedestrian Injuries in Deprived Communities. PLoS ONE 8(4): e60158. doi:10.1371/journal.pone.0060158. Full text link

REYNOLDS C, Harris M, Teschke K, Cripton P, Winters M. (2009) The impact of transportation infrastructure on bicycling injuries and crashes: a review of the literature. Environmental Health, 8:47 doi:10.1186/1476-069X-8-47. Full text link

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#PHTwitJC26 Evidence, Ethics & Values in Health Promotion -Intro post

On Monday 1st July we are discussing this paper:

CARTER, Stacy M., Lucie Rychetnik, Beverley Lloyd, Ian H. Kerridge, Louise Baur, Adrian Bauman, Claire Hooker, and Avigdor Zask. (2011) Evidence, Ethics, and Values: A Framework for Health Promotion. American Journal of Public Health, Vol. 101, No. 3, pp. 465-472. doi: 10.2105/AJPH.2010.195545  http://ajph.aphapublications.org/doi/full/10.2105/AJPH.2010.195545

How to join in

Our live chat starts at 8.00 pm (BST) on Twitter and lasts for an hour. Join in and /or follow by using the hashtag #PHTwitJC. If you’ve never joined a Twitter chat before, see the ‘About’ tab above for some tips. Our ‘club’ is completely open – anyone can join in. If you miss the live hour, we will archive any comments / responses posted on the hashtag within the following 24 hours. Chats are summarised and archived here on the blog.

Introduction to the paper and questions for discussion

The issues

Ethical principles related to biomedicine are routinely referred to to guide clinical and research practice.  While there are areas of debate and contention, ethics is well-established as an area of discussion in professions allied to medicine, and related research. However, until relatively recently, ethics in public health and specifically, health promotion, were addressed only implicitly. Frameworks from biomedical ethics, such as appeal to principles of autonomy, beneficence, non-maleficence and  justice, are of limited benefit when considering the scope of health promotion actions:

“Under what circumstances, for example, would a health promotion perspective suggest that autonomy should be overridden in the interest of the greater good? What is health promotion’s response when considerations of social justice conflict with rights or the maximization of health gain?”  (Sindall, 2002)

Evidence and ethics

In the article we are discussing, Carter et al propose that the evidence base and ethics base within health promotion practice /evaluation must be linked and underpinned by values. The role of evidence to inform health promotion is problematised.

While many interventions are applied with little underpinning evidence of effectiveness, growing awareness of the need for robust evidence has, they claim, led to a skewing of focus towards individual-level behaviour change interventions which are more amenable to evaluation using a trial design. Furthermore, they illustrate how   there is little agreement within public health practice about the most desirable outcomes – for example, which is the more important- fitness, or body weight?

The authors identify two  ethically-relevant concepts for consideration in body weight interventions.

Coercion may occur where choices and liberties are constrained (e.g. via structural interventions), or, the authors argue, where the public are manipulated or exposed to  fear about risk, in order to initiate behaviour change.

Stigmatization occurs where individuals are linked to negative stereotypes; it can have serious, negative consequences for individuals’ sense of self. (  Weight stigma is a growing area of concern – see e.g. this recent conference on the issue).

They illustrate the discussion with the example of interventions regarding body weight. The specific case study used is an Australian social marketing campaign, Measure Up. The TV campaign adverts analysed can be viewed:

Ad 1

The second advertisement is available here: Ad 2.

Developing a framework

Carter et al propose a framework that links their thinking on ethics, evidence and values in health promotion. A key aspect is  the necessity for transparency and reflection about the ethical and evidential values underpinning  a situation or intervention.

They then apply their framework to the ‘Measure Up’ campaign using the concepts of stigma and coercion:

Carter Ethics Framework fig 2

Their results indicate that the ethical and evidential underpinnings of the campaign are questionable:

“Might the campaign be unreasonably coercive, encouraging unjustifiable fear, self-surveillance, self-loathing, or sense of failure?”

Conclusions

Overall, the authors present their framework as a set of ‘thinking tools’ to guide practice in health promotion, with a particular focus on transparency regarding ethical priorities in specific practice situations. They suggest that further ‘ethically relevant concepts’ need have their dimensions specified in the same way that stigmatization and coercion were addressed in this paper.

Questions for journal club:

1) Are the aims clear?
2) Who will be affected by these results? What is the scope?
3) Was the development of their framework justified and clearly explained?

4) Was the application of the framework to the case study (‘How do you measure up?’) transparent and reasonable?
5) What are the implications for policy/practice?

Further reading

If you are interested in further reading on public health ethics, try these books:

  • Dawson, A. (ed.) (2011) Public Health Ethics: key concepts and issues in policy and practice. Cambridge: Cambridge University Press.. Cambridge: Cambridge University Press.
  • Peckham, Stephen; Hann, Alison (eds) (2010) Public Health: ethics and practice. Bristol: Policy Press

The journal, Public Health Ethics also has many interesting articles. It is  a subscription journal, but carries occasional open-access papers  (including one of the choices in our Poll for this topic).

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Confirmed Ethics paper for #PHTwitJC 26

imageThe winner of our poll for the next paper to discuss is:

CARTER, Stacy M., Lucie Rychetnik, Beverley Lloyd, Ian H. Kerridge, Louise Baur, Adrian Bauman, Claire Hooker, and Avigdor Zask. (2011) Evidence, Ethics, and Values: A Framework for Health Promotion. American Journal of Public Health, Vol. 101, No. 3, pp. 465-472. doi: 10.2105/AJPH.2010.195545 http://ajph.aphapublications.org/doi/full/10.2105/AJPH.2010.195545

The journal club chat will take place on Monday 1st July from 8.00 pm (BST). An introductory post and some questions will be up on the blog a few days before.

We’re looking forward to chatting on ethics in public health – all welcome to join us.

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Ethics in Public Health -vote for a paper #PHTwitJC 26

Next #PHTwitJC journal club live chat will take place on Monday 1st July at 2000-2100 hrs (British Summer Time). All are welcome.

Ethics logo

The topic is ethics in public health.  As  befits the topic, the papers selected for the poll (all open access) are review-type /theoretical articles rather than primary research studies. Each of the papers does discuss ethics in relation to a specific public health topic.

Please vote for your favoured paper for discussion. Full citations and URLs are listed below the poll.  Voting will close late on Wednesday 26th June.  

Full references & links

CARTER, Stacy M., Lucie Rychetnik, Beverley Lloyd, Ian H. Kerridge, Louise Baur, Adrian Bauman, Claire Hooker, and Avigdor Zask. (2011) Evidence, Ethics, and Values: A Framework for Health Promotion. American Journal of Public Health, Vol. 101, No. 3, pp. 465-472. doi: 10.2105/AJPH.2010.195545  http://ajph.aphapublications.org/doi/full/10.2105/AJPH.2010.195545

HAVE, Marieke, Inez D de Beaufort, Johan P Mackenbach and Agnes van der Heide (2010). An overview of ethical frameworks in public health: can they be supportive in the evaluation of programs to prevent overweight? BMC Public Health 10:638. doi:10.1186/1471-2458-10-638  http://www.biomedcentral.com/1471-2458/10/638

SELGELID, Michael J. (2008). Ethics, Tuberculosis and Globalization, Public Health Ethics 1(1): 10-20 doi:10.1093/phe/phn001  http://phe.oxfordjournals.org/content/1/1/10.full

SINGH Jerome, A. (2012) Why Human Health and Health Ethics Must Be Central to Climate Change Deliberations. PLoS Medicine 9(6): e1001229. doi:10.1371/journal.pmed.1001229   http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001229

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Evaluation Survey #PHTwitJC

We’ve had a great second year with 25 successful Journal Club sessions and over 10,000 hits to our website (https://phtwitjc.wordpress.com/) since we started in 2011.  We are incredibly grateful for all the support, discussions and ideas generated by #PHTwitJC participants.

We’ve taken on board last years feedback; we’ve varied the time and day of #PHTwitJC discussions, chosen topics which you were most interested in, we’ve increased the time between poll, paper announcement and discussion, and we’re planning our first guest chair for later this year.  Have these changes worked for you? What else can we do?

This quick evaluation survey should take 5-10 minutes to complete, and your feedback will help to shape #PHTwitJC moving into it’s third year of operation.  So whether you’re a frequent contributor, occasional observer, or have never participated – we want to hear about how we can make #PHTwitJC work for you!

Very best wishes,

Caroline & Kate (#PHTwitJC Co-founders)

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Summary of #PHTwitJC 25: Alcohol price and drinking behaviour

alcOn Thursday 23rd May #PHTwitJC discussed the following paper:

A C Wagenaar et al (2009) Effects of beverage alcohol price and tax levels on drinking: a meta-analysis of 1003 estimates from 112 studies, Addiction, 104, 179–190 PDF

The full transcripts can be found on our archive page, however I’ve tried to summarise some of the key debates below.

1 – Were the aims of this study clear?

Although we all understood what that authors were hoping to achieve in this study, it was noted that the aims were not explicitely stated by the authors.  An important observation was made by @DotBirch:

@PHTwitJC as often seen with sys revs – the aim is in the abstract but not explicit in the paper (although I am fast
reading!) #PHTwitJC

@rebeccahams noted that the target population was not clearly defined.  Also, some commented that the outcomes were complex and not clearly defined (e.g. the authors did not explain how they were measuring drinking behaviour).  For example @rebeccahams tweeted:

#PHTwitJC my concern was about the difference in alcohol intake/attitudes in different countries and how that might affect pricing polices

2 – Was the systematic review comprehensive?

It was noted that the authors had not followed PRISMA guidelines for reporting methods of systematic reviews.  For example @dotbirch tweeted:

 
@PHTwitJC missing: flowchart and summary table? would have made reading much easier #PHTwitJC

@Fibigibi13 added:

 
@dotbirch @PHTwitJC #PHTwitJC And would have reduced the need to miss out detail in a lengthy narrative. (If word limits are an issue).

Overall we agreed that the review was comprehensive from what was written, but noted that the presentation of such information could’ve been improved through abiding to the PRISMA guidelines.

3 – Were any adjustments made for study size or quality?

This wasn’t very clear.  There was no information on data extraction nor quality assessment, and although some information was provided it was laid out in the narrative text rather than in tables or graphs.

@PHTwitJC #PHTwitJC YES!!! I found it very difficult to read being embedded in the text. Tables, charts, graphs, please!
@Fibigibi13 I would echo this feedback – find formulae hard to judge, but charts / graphs much easier to understand and interpret #PHTwitJC

As @DotBirch noted, adjustment for study size was done:

@PHTwitJC they have checked homogenieity and used both i and Q tests would take into account study size #statsnightmare #PHTwitJC

4 – Do you believe the results? Could anything else explain these findings?

The results of the paper show a strong statistically significant association, and can be summarised as follows:

@PHTwitJC however the results are #lush #PHTwitJC

@KateT_health tweeted:

@PHTwitJC I’m not totally confident in that given the elisions etc and lack of clarity in data. But I’d like to think it’s right! #PHTwitJC

Some further information would be useful to be able to more fully interpret these results.  Suggestions included controlling for potential confounders such as: general living costs, GDP, sub-group analysis… and looking at potential bias, e.g. definition and measures of ‘drinking behaviour’.

5 – What implications do the findings have for public health practice & policy?

The results of the paper suggest a strong association between alcohol pricing and drinking behaviour, which adds to the evidence that a population-level intervention for minimising alcohol misuse.  @DotBirch suggested:

@PHTwitJC i hope cameron reads it and does a U U turn on minimum pricing! #PHTwitJC

…to which @matandbec agreed:

@PHTwitJC I’ll raise a glass (containing no more than 3-4 units) to that #PHTwitJC

Following the lively discussion and debate we reflected upon the importance of communicating key messages from research, as well as being transparant in the methods used to derive at those messages.  As @PHTwitJC tweeted:

Interesting to reflect not just on what the results show and what that means, but how key #PublicHealth messages are communicated #PHTwitJC
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Time To Change stigma and discrimination: evaluation results

Mental health is an important public health topic. Mental health problems constitute a large proportion of the worldwide burden of disease; therefore establishing services for prevention and treatment according to need are priority areas for public health.

It is increasingly being recognised that both mental and physical health concerns should be treated with equal importance (parity of esteem).  However this is often easier said than done, as mental health is largely stigmatised and many people with mental health issues face discrimination.

You may recall that in April we critiqued a paper which was part of a series of evaluation papers from the Time To Change campaign.

I did a summary blog for The Lifestyle Elf on all seven of the Time To Change evaluation papers, and thought I would share it with you all.  I leave you with a link to my blog below, and a cartoon strip from the Time To Change campaign. Enjoy!

My blog: Time To Change stigma and discrimination: evaluation results

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#PHTwitJC 25: Does alcohol price affect drinking behaviour?

On Thursday 23rd May at 8pm #PHTwitJC will be discussing this paper:

A C Wagenaar et al (2009) Effects of beverage alcohol price and tax levels on drinking: a meta-analysis of 1003 estimates from 112 studies, Addiction, 104, 179–190 PDF

Why is alcohol a public health issue?

The misuse of alcohol – whether as chronically heavy drinking, binge-drinking or even moderate drinking in inappropriate circumstances (e.g. operating machinery, on medication) – not only poses a threat to the health and wellbeing of the drinker, but also to family, friends,  communities and wider society through such problems as crime, anti-social behaviour and loss of productivity. It is also directly linked to a range of health issues such as high blood pressure, mental ill-health, accidental injury, violence, liver disease and sexually transmitted infection.

There are various options to try and reduce alcohol misuse including individual approaches (such as support services to identify and help people with alcohol related problems), education (such as the Know Your Limit, and Change4 Life ‘sneaky drinks’ adverts), through to licensing, regulation and legislation.  Setting a minimum-price for alcohol has recently been implemented in Scotland (50 p per unit), and is currently being considered as an option to reduce alcohol misuse in the rest of the UK.

For further information:

Paper Summary:

  • Method: The authors did a systematic review of studies which examined the relationship between measures of beverage alcohol tax or price level, and alcohol sales or self-reported drinking (n = 122 studies found)
  • Analysis: Partial correlations were calculated for each major model or subgroup reported within each study.  Random effects models were used to combine studies for inverse variance.
  • Results: Meta-analytical results showed a relationship which was statistically significant (p<0.001). Aggregate-level r = -0.17 for beer, -0.30 for wine, -0.29 for spirits and -0.44 for total alcohol.

The authors concluded:

A large literature establishes that beverage alcohol prices and taxes are related inversely to drinking.  Effects are large compared to other prevention policies and programs. Public policy that raise prices of alcohol are an effective means to reduce drinking

Discussion Points:

All are welcome to join the discussion at the Twitter Hashtag #PHTwitJC. If you have not joined a Twitter chat before, please see the ‘about’ tab above for some tips.

  1. Were the aims of this study clear? (consider the population, outcome measures, intervention)
  2. Was the systematic review comprehensive? (consider research designs included, inclusion and exclusion criteria, would all relevant studies have been identified?)
  3. Were any adjustments made for study size or quality? (if appropriate)
  4. Do you believe the results? Could anything else explain these findings? (Consider whether the results are due to chance, bias, confounding or the truth?)
  5. What implications do the findings have for public health practice & policy? Do you agree with the authors conclusions?
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